Cocciban is a synergistie potentiated inophore with combination of Monensin @ 8% & Nicarbazin @ 8 % in granular form. Cocciban’s Monensin an inophore & Nicarbazin a chemical coccidiostat offers superior performance and year round protection with its broad spectrum of action against both the mucosal & luminal life cycle stages of coccidial multiplication in intestine
Indications:
For the prevention of coccidiosis in broiler chickens & rearing pullets (up to 16 weeks of age only) caused by Eimeria Fenella, E. acervulina, E.maxima, E. necatrix, E. brunetti, E. mitis and E. praecox
Mechanism of Action:
Cocciban Monensin acts in the intestinal lumen by attaching on coccidial cell membrance causing continuous influx of sodium ions inside the eoccidial cell resulting in concurrent water influx along with sodium ion. Parasitic NA/K pump gets activated to pump out sodium ions outside the protozoal cell. However it cannot cope with continuous influx of sodium & water, resulting in alteration in parasitic osmoregulation with resultant swelling & death of the parasite
Those coccidial cells that escape the Monensin action get acted upon by Cocciban’s Nicarbazin, which enters the coccidial cell in intestinal wall & blocks the energy regulation process of parasitic NA/K pump, thus impairing its activity further resulting in swelling & death of the parasite. Very few parasite cells that remain, activates the immune system & provide longterm protection
Benefits:
- Effective in high eoecidiosis challenge
- Helps in development of immunity against coccidia
- Can be used throughout the year
- Protects Intestinal Integrity
- Prevents coccidiosis to reduce risk of bacterial enteritis
- Broad spectrum of activity
- Granular consistency supports good flowability & dispersion in premises and feed
- Stable in all common methods of processing and preparation of the feed
- Effective complex mechanism of action reduces the risk of resistance development